Univerza na Primorskem Fakulteta za matematiko, naravoslovje in informacijske tehnologije
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ponedeljek, 23. junij 2025 Izdelava matematičnih modelov bioreaktorja: Rezultati sodelovanja z Novartisom//Mathematical Modeling of Bioreactor Processes: Results from the Collaboration with Novartis

V okviru Raziskovalnega Matematičnega Seminarja bodo študentje 2. stopnje UP FAMNIT in UL FMF predstavili rezultate projekta ImmBIO:  Izdelava matematičnih modelov bioreaktorja, ki je potekal od 10. 1. do 9. 6. 2025 v sodelovanju s podjetjem Novartis. Projekt je potekal v okviru javnega razpisa Problemsko učenje študentov v delovno okolje: gospodarstvo, negospodarstvo in neprofitni sektor v lokalnem/regionalnem okolju 2024–2027.

Pod vodstvom delovnih in pedagoških mentorjev so bili študentje razdeljeni v tri skupine in so prek rednih srečanj med drugim raziskovali naslednje teme:

  • CFD modeliranje mešanja v bioreaktorju, vključno s testiranjem turbulentnih modelov (npr. k-ε in LES) ter uporabo sledilcev za oceno homogenizacije medija.

  • Mehanistično modeliranje bioreaktorja, kjer razvijajo 1D modele na osnovi navadnih diferencialnih enačb ter 2D modele s parcialnimi diferencialnimi enačbami, reševane z numeričnimi metodami.

  • Modeliranje SPTFF procesa (enoprehodna tangencialna pretočna filtracija) za analizo in optimizacijo procesnih parametrov.

Kdaj? 23.6.2025, 15.00

Kje? ZOOM: https://upr-si.zoom.us/j/61676101514 

Jezik? Angleščina

At the Mathematical Research Seminar, second-cycle students from UP FAMNIT and UL FMF will present the outcomes of the ImmBIO project, which was conducted from January 10 to June 9, 2025, in collaboration with Novartis. The project focused on the development of mathematical models for bioreactors and was carried out under the public call Problem-Based Learning for Students in the Workplace: Economy, Non-Economy, and Non-Profit Sectors in the Local/Regional Environment 2024–2027.

Under the guidance of academic and industry mentors, the students were organized into three groups and explored several key topics through regular meetings, including:

  • CFD modeling of mixing processes in bioreactors, involving the evaluation of turbulent models such as k-ε and LES, and the use of tracer particles to assess medium homogenization.

  • Mechanistic modeling of bioreactors, developing one-dimensional models based on ordinary differential equations, as well as two-dimensional models using partial differential equations, solved via numerical methods.

  • Modeling of the Single-Pass Tangential Flow Filtration (SPTFF) process to analyze and optimize process parameters.

When? 23.6.2025, 15.00

Where? ZOOM: https://upr-si.zoom.us/j/61676101514 

Language? English